BDBM30019 BMCL181297 Compound 5F::triazolothiadiazine, 5

SMILES COc1ccc(OC)c(c1)-c1nnc2SCC(=Nn12)c1ccc(OC)c(OC)c1

InChI Key InChIKey=DZAUSKKPHXFGNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30019   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
National Human Genome Research Institute

LigandPNGBDBM30019(BMCL181297 Compound 5F | triazolothiadiazine, 5)
Affinity DataIC50: 6.70nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
National Human Genome Research Institute

LigandPNGBDBM30019(BMCL181297 Compound 5F | triazolothiadiazine, 5)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed