BDBM299651 (2R,4R)-2-(2-Aminoacetylamino)-5-(5′-chloro-2′-fluoro-biphenyl-4-yl)-4-[(1H-[1,2,3]triazole-4-carbonyl)amino]pentanoic Acid::US9593110, Example 33

SMILES CB(O)NCC(=O)N[C@H](C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NC(=O)c1c[nH]nn1)C(O)=O

InChI Key InChIKey=IRGMTGNQORAWBZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299651   

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299651(US9593110, Example 33 | (2R,4R)-2-(2-Aminoacetylam...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
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US Patent