BDBM299635 (2R,4R)-5-(5′-Chloro-2′-fluorobiphenyl-4-yl)-4-[(3-ethylisoxazole-5-carbonyl)amino]-2-methoxycarbonylaminopentanoic Acid::US9593110, Example 29

SMILES CCc1cc(on1)C(=O)N[C@@H](C[C@@H](CNC(=O)OC)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F

InChI Key InChIKey=IGBXAYCVVLRWLQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299635   

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299635(US9593110, Example 29 | (2R,4R)-5-(5′-Chloro...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
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US Patent