BDBM299347 (2S,4S)-5-(5′-Chloro-2′-fluorobiphenyl-4-yl)-4-[(3-ethylisoxazole-5-carbonyl)amino]-2-methoxymethylpentanoic Acid::US9593110, Example 1

SMILES CCOC(=O)[C@H](COC)C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NC(=O)c1cc(CC)no1

InChI Key InChIKey=HGQKHNBSYOXEIE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299347   

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299347(US9593110, Example 1 | (2S,4S)-5-(5′-Chloro-...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In DepthDetails
US Patent