BDBM299265 US9593121, I-10::tert-butyl 2-(7-{(1R,3S,4S)-3-hydroxy-4- [(sulfamoyloxy)methyl]cyclopentyl}-7H-pyrrolo[2,3- d]pyrimidin-4-yl)-6-methoxy-1H-indole-1-carboxylate

SMILES COc1ccc2cc(-c3ncnc4n(ccc34)[C@H]3C[C@H](O)[C@H](COS(N)(=O)=O)C3)n(C(=O)OC(C)(C)C)c2c1

InChI Key InChIKey=VRTUMOBMFCLTAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299265   

TargetUbiquitin-like modifier-activating enzyme 6(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM299265(US9593121, I-10 | tert-butyl 2-(7-{(1R,3S,4S)-3-hy...)
Affinity DataIC50: 1.03E+3nMAssay Description:The UBA6 enzmatic reaction totals 20 μL and contains 50 mM HEPES (pH 7.5), 0.05% BSA, 0.02% Tween 20, 0.1 mM TCEP, 5 mM MgCl2, 2 μM ATP, 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent