BDBM297406 3-Amino-6-(4-fluoro-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide::US10117858, Example 7::US20240058315, Example 7

SMILES C[C@](O)(CNC(=O)c1nc(-c2ccc(F)cc2)c(cc1N)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=TZBFDPNSDFVMAL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297406   

LigandPNGBDBM297406(US10117858, Example 7 | 3-Amino-6-(4-fluoro-phenyl...)
Affinity DataEC50:  40nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM297406(US10117858, Example 7 | 3-Amino-6-(4-fluoro-phenyl...)
Affinity DataEC50:  40nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent