BDBM297403 3-Amino-6-methoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (3,3,3-trifluoro-2-hydroxy-propyl)-amide::US10117858, Example 12::US20240058315, Example 12

SMILES COc1nc(C(=O)NCC(O)C(F)(F)F)c(N)cc1C(F)(F)F

InChI Key InChIKey=SGMQDTWKBCOQTJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297403   

LigandPNGBDBM297403(US10117858, Example 12 | 3-Amino-6-methoxy-5-trifl...)
Affinity DataEC50:  35nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM297403(US10117858, Example 12 | 3-Amino-6-methoxy-5-trifl...)
Affinity DataEC50:  35nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent