BDBM297400 US10117858, Example 4::US10117858, Example 6::US20240058315, Example 4

SMILES COc1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F

InChI Key InChIKey=USHQRIKZLHNPQR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 297400   

LigandPNGBDBM297400(US10117858, Example 6 | US10117858, Example 4 | US...)
Affinity DataEC50:  76nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM297400(US10117858, Example 6 | US10117858, Example 4 | US...)
Affinity DataEC50:  426nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM297400(US10117858, Example 6 | US10117858, Example 4 | US...)
Affinity DataEC50:  76nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In DepthDetails
US Patent