BDBM2974 Quinoxalinone deriv. 6s::methyl 2-(2-cyclopropylethynyl)-3-oxo-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylate

SMILES COC(=O)N1c2ccccc2NC(=O)C1(C#CC1CC1)C(F)(F)F

InChI Key InChIKey=MZBDWXUBAMIONF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2974   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2974(methyl 2-(2-cyclopropylethynyl)-3-oxo-2-(trifluoro...)
Affinity DataIC50: 504nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed