BDBM296868 BDBM376119::US10111866, Example 1::US10292975, Example 1::US10709695, Example 1

SMILES CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)C(=O)NCCN(C)C)c(F)c1

InChI Key InChIKey=KKNHFKVMTIMBGM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 296868   

LigandPNGBDBM296868(US10709695, Example 1 | BDBM376119 | US10111866, E...)
Affinity DataIC50: 10nMAssay Description:Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM296868(US10709695, Example 1 | BDBM376119 | US10111866, E...)
Affinity DataIC50: 10nMAssay Description:Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM296868(US10709695, Example 1 | BDBM376119 | US10111866, E...)
Affinity DataIC50: 10nMAssay Description:Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM296868(US10709695, Example 1 | BDBM376119 | US10111866, E...)
Affinity DataIC50: 10nMAssay Description:Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent