BDBM296182 2-[4-[N,4-dimethyl-3-(4-methylpiperazin-1- yl)anilino]phenoxy]pyrido[3,4-d]pyrimidin- 4-ol::US10112940, Example 105::US10202381, Example 105::US10208039, Example 105::US10611763, Example 105::US10815234, Example 105::US11535616, Example 105

SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(c1)N1CCN(C)CC1

InChI Key InChIKey=OPJXGSSNEIRHII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 296182   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296182(US10112940, Example 105 | 2-[4-[N,4-dimethyl-3-(4-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296182(US10112940, Example 105 | 2-[4-[N,4-dimethyl-3-(4-...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent