BDBM296181 2-(1-piperidin-4-ylindol-5- yl)oxypyrido[3,4-d]pyrimidin-4-ol::US10112940, Example 104::US10202381, Example 104::US10208039, Example 104::US10611763, Example 104::US10815234, Example 104::US11535616, Example 104

SMILES Oc1nc(Oc2ccc3n(ccc3c2)C2CCNCC2)nc2cnccc12

InChI Key InChIKey=AVPBNCDXCUBCFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 296181   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296181(US10112940, Example 104 | 2-(1-piperidin-4-ylindol...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296181(US10112940, Example 104 | 2-(1-piperidin-4-ylindol...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent