BDBM296095 2-(4-{methyl-[3-(4-methyl-piperazin-1-yl)- phenyl]-amino}-phenoxy)-pyrido[3,4-d] pyrimidin-4-ol::US10112940, Example 22::US10112940, Example 79::US10202381, Example 79::US10208039, Example 79::US10611763, Example 79::US10815234, Example 79::US11535616, Example 22

SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(c1)N1CCN(C)CC1

InChI Key InChIKey=NVRHIDHPBHNKJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 296095   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296095(US10112940, Example 22 | US10112940, Example 79 | ...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296095(US10112940, Example 22 | US10112940, Example 79 | ...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296095(US10112940, Example 22 | US10112940, Example 79 | ...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296095(US10112940, Example 22 | US10112940, Example 79 | ...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent