BDBM295750 US10112935, Compound A-50

SMILES O=C(Nc1cccc(c1)-c1nnc(Nc2ccc3[nH]ncc3c2)s1)c1cccnc1

InChI Key InChIKey=HDFRUDLFBIVZMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 295750   

TargetRho-associated protein kinase 1(Human)
Lycera

US Patent
LigandPNGBDBM295750(US10112935, Compound A-50)
Affinity DataIC50: 3.00E+4nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Lycera

US Patent
LigandPNGBDBM295750(US10112935, Compound A-50)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent