BDBM2956 3-(2-cyclopropylethynyl)-4-(cyclopropylmethyl)-3-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-2-one::Quinoxalinone deriv. 6a

SMILES FC(F)(F)C1(C#CC2CC2)N(CC2CC2)c2ccccc2NC1=O

InChI Key InChIKey=LVTDIDQSIGPRAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2956   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2956(3-(2-cyclopropylethynyl)-4-(cyclopropylmethyl)-3-(...)
Affinity DataIC50: 253nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed