BDBM293898 (S)-3-(2- Cyclopropylpyrimidin-5- yl)-1-(3-fluoro-2- methylphenyl)-N- hydroxycyclopent-2- enecarboxamide::US10106535, Example 24::US9617259, 24

SMILES Cc1c(F)cccc1[C@@]1(CCC(=C1)c1cnc(nc1)C1CC1)C(=O)NO

InChI Key InChIKey=LXFQZWLCATUSEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293898   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293898(US10106535, Example 24 | (S)-3-(2- Cyclopropylpyri...)
Affinity DataIC50: 20nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293898(US10106535, Example 24 | (S)-3-(2- Cyclopropylpyri...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In DepthDetails
US Patent