BDBM291312 US9580432, Example 43

SMILES Nc1ncnc2n(nc(C(=O)Nc3nc4cc(ccc4o3)C(F)(F)F)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=ZQFXXYFWVJJNKC-LLVKDONJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291312   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291312(US9580432, Example 43)
Affinity DataIC50: 0.546nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent