BDBM291298 US9580432, Example 29

SMILES Cc1ccc2oc(NC(=O)c3nn([C@@H]4CCN(C4)C(=O)C=C)c4ncnc(N)c34)nc2c1

InChI Key InChIKey=OFFIMCWOYWWMQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291298   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291298(US9580432, Example 29)
Affinity DataIC50: 0.485nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent