BDBM291292 US9580432, Example 23

SMILES Cc1cc2nc(NC(=O)c3nn([C@@H]4CCCN(C4)C(=O)C=C)c4ncnc(N)c34)oc2cc1C

InChI Key InChIKey=IDKTVJOAWRRCQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291292   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291292(US9580432, Example 23)
Affinity DataIC50: 1.58nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent