BDBM291286 US9580432, Example 17

SMILES CCN(CC)C\C=C\C(=O)N1CCC[C@H](C1)n1nc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12

InChI Key InChIKey=JTMWQUYZSGIWPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291286   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291286(US9580432, Example 17)
Affinity DataIC50: 0.811nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291286(US9580432, Example 17)
Affinity DataIC50: 157nMpH: 7.5 T: 2°CAssay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against EGFR kinase activity in vitro, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
Go to US Patent