BDBM291270 (R)-tert-butyl 3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate::US9580432, Example 1

SMILES Nc1ncnc2n(nc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=GAENTFUDVGFXEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291270   

TargetTyrosine-protein kinase BTK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291270(US9580432, Example 1 | (R)-tert-butyl 3-(4-amino-3...)
Affinity DataIC50: 0.415nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
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