BDBM291170 2-[N-(Propan-2-yl)(4-fluorobenzene)sulfonamido]-N-([6-[4-(trifluoromethyl)cyclohex-1-en-1-yl]pyrimidin-4-yl]methyl)acetamide::US9580411, Example 85

SMILES CC(C)N(CC(=O)NCc1cc(ncn1)C1=CCC(CC1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=UBMQUDZBOKUCFG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291170   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hoffmann-La Roche

US Patent

LigandBDBM291170(2-[N-(Propan-2-yl)(4-fluorobenzene)sulfonamido]-N-...)Copy SMILESCopy InChI

Affinity DataIC50: 13nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2019
Entry Details
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