BDBM291168 2,2-Dideuterio-2-(4-fluoro-N-isopropylphenylsulfonamido)-N-((6-(6-(trifluoromethyl)pyridin-3-yl)pyrimidin-4-yl)methyl)acetamide::US9580411, Example 83

SMILES CC(C)N(CC(=O)NCc1cc(ncn1)-c1ccc(nc1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=USAKNJFJFIOYMS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291168   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hoffmann-La Roche

US Patent

LigandBDBM291168(2,2-Dideuterio-2-(4-fluoro-N-isopropylphenylsulfon...)Copy SMILESCopy InChI

Affinity DataIC50: 58nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2019
Entry Details
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