BDBM29008 (2R)-2-[(5-chloro-2-fluorophenyl)(4-chlorobenzene)sulfonamido]propyl N-[3-(1H-imidazol-1-yl)propyl]carbamate::Carbamate-appended N-alkylsulfonamide, 51
SMILES C[C@H](COC(=O)NCCCn1ccnc1)N(c1cc(Cl)ccc1F)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=HKLRXCRZQQZDET-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 29008
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Human)
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataEC50: 0.660nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair