BDBM290002 2-Methoxy-2-methyl-1-(4-{6- [5-(2H-pyrazol-3-yl)-pyridin-2- yloxy]-quinolin-2-ylmethyl}- piperazin-1-yl)-propan-1-one::US9573957, Example 128

SMILES COC(C)(C)C(=O)N1CCN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3n2)CC1

InChI Key InChIKey=PWASYBVCQGFLIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290002   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM290002(2-Methoxy-2-methyl-1-(4-{6- [5-(2H-pyrazol-3-yl)-p...)
Affinity DataIC50: 0.560nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In DepthDetails
US Patent