BDBM289983 (S)-3-Hydroxy-1-(1-{6-[5-(2H- pyrazol-3-yl)-pyridin-2-yloxy]- benzofuran-3-ylmethyl}-piperidin- 4-yl)-pyrrolidin-2-one::US9573957, Example 109

SMILES O[C@H]1CCN(C2CCN(Cc3coc4cc(Oc5ccc(cn5)-c5ccn[nH]5)ccc34)CC2)C1=O

InChI Key InChIKey=SKKWNGNEDXNGEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289983   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289983((S)-3-Hydroxy-1-(1-{6-[5-(2H- pyrazol-3-yl)-pyridi...)
Affinity DataIC50: 0.360nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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