BDBM289975 2-Hydroxy-1-(7-{6-[5-(2H-pyrazol- 3-yl)-pyridin-2-yloxy]-quinolin-2- ylmethyl}-2,7-diaza-spiro[4.4]non- 2-yl)-ethanone::US9573957, Example 102

SMILES OCC(=O)N1CCC2(CCN(Cc3ccc4cc(Oc5ccc(cn5)-c5ccn[nH]5)ccc4n3)C2)C1

InChI Key InChIKey=WBQZLLWZABAXGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289975   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289975(2-Hydroxy-1-(7-{6-[5-(2H-pyrazol- 3-yl)-pyridin-2-...)
Affinity DataIC50: 0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
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US Patent