BDBM289923 1-(1-{(R)-6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]-2,3-dihydro- benzofuran-2-ylmethyl}-piperidin- 4-yl)-pyrrolidin-2-one::US9573957, Example 63

SMILES O=C1CCCN1C1CCN(C[C@H]2Cc3ccc(Oc4ccc(cn4)-c4ccn[nH]4)cc3O2)CC1

InChI Key InChIKey=IFPGAJVLPUNQML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289923   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289923(1-(1-{(R)-6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]...)
Affinity DataIC50: 0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In DepthDetails
US Patent