BDBM289916 (1-Hydroxy-cyclopropyl)-(8-{6-[5- (2H-pyrazol-3-yl)-pyridin-2-yloxy]- quinolin-2-ylmethyl}-3,8-diaza- bicyclo[3.2.1]oct-3-yl)-methanone::US9573957, Example 56

SMILES OC1(CC1)C(=O)N1CC2CCC(C1)N2Cc1ccc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc2n1

InChI Key InChIKey=ZBWPMUSKZANKEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289916   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289916((1-Hydroxy-cyclopropyl)-(8-{6-[5- (2H-pyrazol-3-yl...)
Affinity DataIC50: 0.530nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
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US Patent