BDBM289876 ((S)-1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-naphthalen-2-ylmethyl}- pyrrolidin-3-yl)-methanol::US9573957, Example 18

SMILES OC[C@H]1CCN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3c2)C1

InChI Key InChIKey=WCTSGYVVQJWBBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289876   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289876(((S)-1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-n...)
Affinity DataIC50: 0.760nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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