BDBM289483 1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-yl)-1-(bi- cyclo[1.1.1]pentan-1- yl)-1H-imidazol-2-yl)- 2-methylpropan-1-ol::US10093664, Example 59::US11560366, Example 14

SMILES CC(C)C(O)c1nc(cn1C12CC(C1)C2)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=ZNLWKSRHKZKBQH-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289483   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
The University of Texas System

US Patent
LigandPNGBDBM289483(US10093664, Example 59 | 1-(4-(6-amino-5- (trifluo...)
Affinity DataKd:  0.290nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 12(Human)
The University of Texas System

US Patent
LigandPNGBDBM289483(US10093664, Example 59 | 1-(4-(6-amino-5- (trifluo...)
Affinity DataKd:  0.300nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent