BDBM289465 3-(difluoromethoxy)-5- (1-(3-morpholino- bicyclo[1.1.1]pentan-1- yl)-2-neopentyl-1H- imidazol-4-yl)pyridin- 2-amine::US10093664, Example 41

SMILES CC(C)(C)Cc1nc(cn1C12CC(C1)(C2)N1CCOCC1)-c1cnc(N)c(OC(F)F)c1

InChI Key InChIKey=KLECFLJONOFPJL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289465   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
The University of Texas System

US Patent
LigandPNGBDBM289465(US10093664, Example 41 | 3-(difluoromethoxy)-5- (1...)
Affinity DataKd:  82nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent