BDBM289021 BDBM400246::US10093650, Example 17

SMILES FC(F)(F)CCCCCCn1cc(cn1)[C@@]1(CC(=C(C(=O)N1)n1nn[nH]c1=O)c1ccc2CCCCc2c1)C(F)(F)F

InChI Key InChIKey=SNDCKDWBIKSFEU-VWLOTQADSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289021   

LigandPNGBDBM289021(US10093650, Example 17 | BDBM400246)
Affinity DataIC50: 5nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM289021(US10093650, Example 17 | BDBM400246)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM289021(US10093650, Example 17 | BDBM400246)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In DepthDetails
US Patent