BDBM288683 (E)-3-(4-((6S,8R/6R,8S)-7-(2-fluoro-2-methylpropyl)-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)phenyl)acrylic acid::US10087191, Example 101

SMILES CC1Cc2c(ccc3[nH]ncc23)C(N1CC(C)(C)F)c1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=OEYMFWZLIZCCJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288683   

TargetG-protein coupled estrogen receptor 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM288683((E)-3-(4-((6S,8R/6R,8S)-7-(2-fluoro-2-methylpropyl...)
Affinity DataIC50: 3.14nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair
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US Patent