BDBM288325 US10087187, Compound 15

SMILES Cc1c(Cc2c(CO)nc3c(cc(nn23)N2CCOCC2)C(N)=O)cccc1C(F)(F)F

InChI Key InChIKey=QFNURTIELMJFQR-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 288325   

LigandPNGBDBM288325(US10087187, Compound 15)
Affinity DataKd:  1.10E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288325(US10087187, Compound 15)
Affinity DataKd:  7nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288325(US10087187, Compound 15)
Affinity DataKd:  479nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288325(US10087187, Compound 15)
Affinity DataKd:  2.00E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288325(US10087187, Compound 15)
Affinity DataKd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent