BDBM288314 US10087187, Compound 7

SMILES Cc1nc2c(cc(nn2c1Cc1cccc(c1C)C(F)(F)F)N1CCOCC1)-c1ncc[nH]1

InChI Key InChIKey=VOSDZDJRWIFXRH-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 288314   

LigandPNGBDBM288314(US10087187, Compound 7)
Affinity DataKd: >3.31E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288314(US10087187, Compound 7)
Affinity DataKd:  15nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288314(US10087187, Compound 7)
Affinity DataKd:  525nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM288314(US10087187, Compound 7)
Affinity DataKd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288314(US10087187, Compound 7)
Affinity DataKd: >1.00E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In DepthDetails
US Patent