BDBM288053 N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3-methoxy-2'- methyl-1',8'-dioxo- 1',2',3',8'- tetrahydrospiro[1,2-a]pyrazine]- 1,4'-pyrido[1,2-a]pyrazine]- 7'-carboxamide hydrochloride::US10087178, Example S13

SMILES CO[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F

InChI Key InChIKey=ADNMWHFULCNNMU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288053   

TargetProtein Nef(HIV-1)
Japan Tobacco

US Patent
LigandPNGBDBM288053(N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3-methoxy...)
Affinity DataEC50:  4.5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent