BDBM287933 N-(2-(6-chloropyridin-2-yl)-2- phenylethyl)-2-(p-tolyl)quinazolin-4- amine::US10087148, Example 1

SMILES Cc1ccc(cc1)-c1nc(NCC(c2ccccc2)c2cccc(Cl)n2)c2ccccc2n1

InChI Key InChIKey=IATQVBSFAXREHN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287933   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287933(N-(2-(6-chloropyridin-2-yl)-2- phenylethyl)-2-(p-t...)
Affinity DataEC50:  380nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
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