BDBM287168 US9567339, Example A.1.19

SMILES COC(=O)c1cccc(c1)-c1cc2c(ccc(C(N)=O)c2[nH]1)-c1cccc(NC(=O)C=C)c1C

InChI Key InChIKey=SDPKIOCIYUKCGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287168   

TargetTyrosine-protein kinase BTK [393-659](Human)
Abbvie

US Patent
LigandPNGBDBM287168(US9567339, Example A.1.19)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In DepthDetails
US Patent