BDBM2871 US8524710, 53

SMILES CC(C)(C)N1CCN(CC1)c1ccc(c(Cl)c1)S(=O)(=O)[C@H]1CCN(C1)c1nc(ncc1C(=O)NCC(F)(F)F)C#N

InChI Key InChIKey=QWXAIQACRDMYIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2871   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM2871(US8524710, 53)
Affinity DataIC50: 2.35nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
Go to US Patent