BDBM2869 3-(5-chloropyridin-2-yl)-1-[3-(2,6-difluorophenyl)-3-oxopropyl]thiourea::PETT deriv. 19

SMILES Fc1cccc(F)c1C(=O)CCNC(=S)Nc1ccc(Cl)cn1

InChI Key InChIKey=JAWVBARHNLTQNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2869   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2869(3-(5-chloropyridin-2-yl)-1-[3-(2,6-difluorophenyl)...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed