BDBM286334 2-(5-(6-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- yl)pyridin-3-yl)propan-2- ol::US9567333, 12

SMILES CC(C)(O)c1cncc(c1)-c1nc2ccc(F)cn2n1

InChI Key InChIKey=XPYMFIVAPXJBDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286334   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286334(2-(5-(6-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- y...)
Affinity DataIC50: 1.07E+3nMAssay Description:CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286334(2-(5-(6-fluoro-[1,2,4] triazolo[1,5-a]pyridin-2- y...)
Affinity DataIC50: 8.33E+3nMAssay Description:CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent