BDBM286307 5-amino-3-(7-ethoxyquinolin-3- yl)-1-(1-methylcyclohexyl)-1H- pyrazole-4-carboxamide MS (ESI) (M + H)+ = 394.7::US9518026, Example 100::US9956214, Compound 1640

SMILES CCOc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C1(C)CCCCC1

InChI Key InChIKey=XIGBSBUACNWRMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 286307   

TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286307(US9518026, Example 100 | 5-amino-3-(7-ethoxyquinol...)
Affinity DataIC50: 4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286307(US9518026, Example 100 | 5-amino-3-(7-ethoxyquinol...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286307(US9518026, Example 100 | 5-amino-3-(7-ethoxyquinol...)
Affinity DataIC50: 9nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent

TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286307(US9518026, Example 100 | 5-amino-3-(7-ethoxyquinol...)
Affinity DataIC50: 6nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent