BDBM286226 3-cyclopropyl-6-fluoro-2- (pyridin-3-yl)imidazo[1,2- a]pyridine::US9518055, Example 28

SMILES Fc1ccc2nc(c(C3CC3)n2c1)-c1cccnc1

InChI Key InChIKey=JZHFBFYLCYWYRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286226   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286226(US9518055, Example 28 | 3-cyclopropyl-6-fluoro-2- ...)
Affinity DataIC50: 23.4nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286226(US9518055, Example 28 | 3-cyclopropyl-6-fluoro-2- ...)
Affinity DataIC50: 76nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent