BDBM286225 7-fluoro-2-(5-fluoropyridin-3- yl)-3-methylimidazo[1,2- a]pyridine::US9518055, Example 26

SMILES Cc1c(nc2cc(F)ccn12)-c1cncc(F)c1

InChI Key InChIKey=PZYANYLFDCQIJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286225   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286225(US9518055, Example 26 | 7-fluoro-2-(5-fluoropyridi...)
Affinity DataIC50: 4.70nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286225(US9518055, Example 26 | 7-fluoro-2-(5-fluoropyridi...)
Affinity DataIC50: 912nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent