BDBM286067 2-(Difluoromethyl)-5-(((2-fluoro-2-methyl-propanoyl)amino)methyl)-N-(2-(3-(trifluoromethyl)phenyl)benzo[d]oxazol-5-yl)nicotinamide::US10081629, Example 56

SMILES CC(C)(F)C(=O)NCc1cnc(C(F)F)c(c1)C(=O)Nc1ccc2oc(nc2c1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=DQIYOBKUQYSWFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286067   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286067(US10081629, Example 56 | 2-(Difluoromethyl)-5-(((2...)
Affinity DataIC50: 7.74nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286067(US10081629, Example 56 | 2-(Difluoromethyl)-5-(((2...)
Affinity DataIC50: 27.5nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent