BDBM286049 2-Chloro-N-(2-(4-fluorophenyl)-1-methyl-1H-indol-5-yl)-5-(((1-(trifluoromethyl)cyclopropanecarbonyl)amino)methyl)benzamide::US10081629, Example 34

SMILES Cn1c(cc2cc(NC(=O)c3cc(CNC(=O)C4(CC4)C(F)(F)F)ccc3Cl)ccc12)-c1ccc(F)cc1

InChI Key InChIKey=YMORZEHXQIARML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286049   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286049(US10081629, Example 34 | 2-Chloro-N-(2-(4-fluoroph...)
Affinity DataIC50: 7.75nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286049(US10081629, Example 34 | 2-Chloro-N-(2-(4-fluoroph...)
Affinity DataIC50: 12.2nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent