BDBM286044 2-(Difluoromethyl)-5-(((2-fluoro-2-methyl-propanoyl)amino)methyl)-N-(1-(2-methoxyethyl)-2-(4-(trifluoromethyl)phenyl)-1H-indol-5-yl)nicotinamide::US10081629, Example 27

SMILES COCCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)F)cnc3C(F)F)ccc12)C1=CC=C(CC1)C(F)(F)F

InChI Key InChIKey=YUFPBTOOZAZZOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286044   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286044(US10081629, Example 27 | 2-(Difluoromethyl)-5-(((2...)
Affinity DataIC50: 4.77nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286044(US10081629, Example 27 | 2-(Difluoromethyl)-5-(((2...)
Affinity DataIC50: 13.4nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent