BDBM286039 2-Chloro-5-((2,2-dimethylpropanoylamino)methyl)-N-(2-(4-(trifluoromethyl)phenyl)benzo[d]oxazol-5-yl)benzamide::US10081629, Example 22

SMILES CC(C)(C)C(=O)NCc1ccc(Cl)c(c1)C(=O)Nc1ccc2oc(nc2c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WDRKPGCKEBHSIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286039   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286039(US10081629, Example 22 | 2-Chloro-5-((2,2-dimethyl...)
Affinity DataIC50: 6.69nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286039(US10081629, Example 22 | 2-Chloro-5-((2,2-dimethyl...)
Affinity DataIC50: 38.8nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent