BDBM286038 N-(2-(4-Chlorophenyl)-1-methyl-1H-indol-5-yl)-2-(difluoromethyl)-5-(((1-(trifluoromethyl)cyclopropanecarbonyl)amino)methyl)nicotinamide::US10081629, Example 21

SMILES Cn1c(cc2cc(NC(=O)c3cc(CNC(=O)C4(CC4)C(F)(F)F)cnc3C(F)F)ccc12)-c1ccc(Cl)cc1

InChI Key InChIKey=QAGDAXMFCSWXLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286038   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286038(US10081629, Example 21 | N-(2-(4-Chlorophenyl)-1-m...)
Affinity DataIC50: 8.24nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286038(US10081629, Example 21 | N-(2-(4-Chlorophenyl)-1-m...)
Affinity DataIC50: 57.4nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent